Background:
@EN Topical vitamine D3 analogues have been reported to be an effective treatment in patients with psoriasis. Calcipotriol, a new tivamin D3 analogue, is effective and at least 100 times less calcemic than calcitriol.
@ES Objective:
@EN Our purpose was to study the clinical efficacy, safety and tolerability of calcipotriol ointment in the treatment of psoriasis.
@ES Methods:
@EN Twenty five patients with chronic psoriasis were treated with calcipotriol ointment(50㎍/g) twice dilay. Efficacy as measured by the clinical degree of erythema, scale and thickness of lesions, and safety were assessed every 2 weeks.
@ES Results:
@EN The total score of erythema, scale and thickness of the lesions decreased in 6 weeks from 8.52±0.76 to 3,80±1.7 with calcipotriol. Some patients developed mild and transient local side effects. The laboratory tests including serum calcium
remained
unchanged.
@ES Conclusion:
@EN Topical application of calcipostriol ointment for 6 weeks was found to be an effective and safe treatment of psoriasis vulgaris. (Kor J Dermatol 1994 ; 32(4) : 655~661).
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